Here's Who Might Want to Prevent the J&J COVID Shot

Patients with a prior history of an episode of an immune-mediated syndrome identified by thrombocytopenia and apoplexy, such as heparin-induced thrombocytopenia, ought to prevent the Johnson & Johnson COVID-19 vaccine in the instant consequences of their illness, CDC staff said in a call with clinicians Tuesday.

Since the etiology of apoplexy and thrombocytopenia syndrome (TTS) appears comparable to heparin-induced thrombocytopenia, patients with a similar immune-mediated syndrome ought to be provided another FDA-authorized COVID-19 vaccine for a minimum of 90-180 days after their disease solves.

While women under age 50 can get any authorized COVID-19 vaccine, they have an increased risk of TTS connected with the Johnson & Johnson vaccine. CDC personnel noted they should “understand the rare risk of TTS” and may choose one of the other authorized vaccines, such as the mRNA vaccines from Pfizer and Moderna.

Nevertheless, there were no such cautions for patients with danger elements for venous thromboembolism (VTE), or a previous history of thromboses not related to thrombocytopenia. CDC personnel kept in mind the biologic systems for VTE and arterial thrombi were different from the “underlying immune system” for heparin-induced thrombocytopenia.

For that reason, these patients were unlikely to be at increased risk for TTS, they said.

Pregnant women can also receive the Johnson & Johnson COVID-19 vaccine. While apoplexy threat is higher during pregnancy and postpartum, in addition to with hormone contraception, “professionals think these elements do not make individuals more vulnerable to TTS,” CDC personnel noted.

Sara Oliver, MD, of the CDC, prompted people taking aspirin or anticoagulants as part of their routine medications to not stop taking them prior to the Johnson & Johnson COVID-19 vaccine, nor must individuals begin taking these medications prior to getting Johnson & Johnson or any other COVID-19 vaccine.

Clinicians asked whether patients with a history of stroke or risk aspects for stroke should avoid the vaccine. Oliver stated due to the fact that the phenomenon appears to be immune-mediated, “individuals who have a history of other embolic events, consisting of stroke, do not appear to be at increased danger for developing” TTS, and there were no suggestions for individuals with a history of stroke to prevent this vaccine.

Likewise, those with other risk elements, such as smoking cigarettes or obesity, did not seem at increased risk of establishing these unusual blood clots.

Oliver included that CDC has partnered with the American Society of Hematology about medical diagnosis of TTS and treatment-specific suggestions for patients.

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  Molly Walker is deputy handling editor and covers contagious diseases for MedPage Today. She is a 2020 J2 Accomplishment Award winner for her COVID-19 protection. Follow

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