Hair Products and Breast Cancer; CRS After COVID Vax; Good Bacteria and Chemo

Researchers found that moderate use of hair relaxers — products commonly used by Black women and that can contain estrogens or estrogen-disrupting compounds — did not increase the overall risk of breast cancer. (Boston University School of Medicine, Carcinogenesis).

A colorectal cancer patient on anti-PD-1 monotherapy developed cytokine release syndrome (CRS) 5 days after receiving Pfizer’s COVID-19 vaccine, the timing of which suggests a vaccine-related adverse event. (Nature Medicine)

The artificial intelligence-enabled Galen breast cancer diagnostic platform has received CE mark approval, Israel-based Ibex announced.

Even cancer patients who are insured, college-educated, and have above-average income may avoid follow-up care because of the cost. (Medical College of Georgia at Augusta University, Cancer Medicine)

Apellis announced that the phase III PRINCE trial of newly approved pegcetacoplan (Empaveli) versus standard of care in patients with treatment-naive paroxysmal nocturnal hemoglobinuria met its co-primary endpoints.

The U.S. Supreme Court has declined to review a federal appeals court ruling that added two American scientists as joint inventors of PD-1 checkpoint inhibitors, for which a Japanese immunologist received a Nobel Prize. (Reuters)

Scientists found that certain types of gut bacteria can protect other good bacteria from the toxic affects of cancer treatments and mitigate any harmful changes to the gut microbiome. (Northwestern University, mSphere)

FDA granted breakthrough therapy designation to a combination of defactinib and VS-6766, an investigational dual inhibitor of the RAF/MEK pathway, for the treatment of low-grade serous ovarian cancer, Verastem Oncology announced.

Consumption of advanced glycation end products — found in foods that undergo prolonged high-heat processing, such as through deep frying, grilling, or broiling — was associated with increased gallbladder cancer risk, but an inverse association was found with liver cancer. (International Journal of Cancer)

Instead of being driven by random mutations, is cancer actually a type of genetic throwback that is pre-existent and latent in normal cells? (Arizona State University, BioEssays).

Researchers at the Cleveland Clinic have identified the protein hexose-6-phosphate dehydrogenase (H6PD) as a promising target for the prevention and treatment of aggressive, drug-resistant prostate cancer. (Cleveland Clinic, Science Translational Medicine)

Last Updated May 27, 2021

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  Mike Bassett is a staff writer focusing on oncology and hematology. He is based in Massachusetts.

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